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<table class="confluenceTable">


<tr><td>Name</td><td>

Incidence of End-Stage Kidney Disease (ESKD), by Primary Diagnosis

</td></tr>

<tr><td>Short/Other Names</td><td>

Not applicable

</td></tr>


<tr><td>Description</td><td>

Breakdown by primary diagnosis of all incident patients (new patients) with end-stage kidney disease who began renal replacement therapy (RRT) (either dialysis or renal transplantation) for the first time in the calendar year

</td></tr>

<tr><td>Interpretation</td><td>

Increasing incidence rates over time have important implications for resources, disease management and the need for kidney donation.

</td></tr>

<tr><td>HSP Framework Dimension</td><td>

Health System Outcomes: Improve health status of Canadians

</td></tr>

<tr><td>Areas of Need</td><td>

Not applicable

</td></tr>

<tr><td>Geographic Coverage</td><td>

All provinces/territories except Quebec

</td></tr>


<tr><td>Reporting Level/Disaggregation</td><td>

Province/Territory, Breakdown by sex, breakdown by age categories

</td></tr>



<tr><td>Indicator Results</td><td>

Incident End-Stage Renal Disease (ESRD) Patients by Primary Diagnosis

</td></tr>

</table>

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<div role="button" class="expandableTitle" aria-controls="identifyingInfoRegion">Identifying Information</div>

<table id="identifyingInfoRegion">

<tr><td>Name</td><td>

Incidence of End-Stage Kidney Disease (ESKD), by Primary Diagnosis

</td></tr>

<tr><td>Short/Other Names</td><td>

Not applicable

</td></tr>
</table>



<div role="button" class="expandableTitle" aria-controls="descAndCalRegion">Indicator Description and Calculation</div>

<table id="descAndCalRegion">

<tr><td>Description</td><td>

Breakdown by primary diagnosis of all incident patients (new patients) with end-stage kidney disease who began renal replacement therapy (RRT) (either dialysis or renal transplantation) for the first time in the calendar year

</td></tr>

<tr><td>Calculation: Description</td><td>

Counts and rates are based on patients registered during a given calendar year in a Canadian facility. Patients who began RRT for ESKD outside of Canada but are subsequently treated in Canada are included in prevalence counts but not incidence counts.

</td></tr>

<tr><td>Calculation: Geographic Assignment</td><td>

Place of service

</td></tr>

<tr><td>Calculation: Type of Measurement</td><td>

Rate - Per 1,000,000

</td></tr>

<tr><td>Calculation:  Adjustment Applied</td><td>

None

</td></tr>


<tr><td>Calculation:  Method of Adjustment</td><td>

Not applicable

</td></tr>

<tr><td>Denominator</td><td>

Description:
Canadian population
Inclusions:
All Canadians currently residing in Canada
Exclusions:
Not applicable

</td></tr>

<tr><td>Numerator</td><td>

Description:
Patients registered in the Canadian Organ Replacement Register (CORR) who started RRT for ESKD
Inclusions:
Patients registered in CORR during a given calendar year (January 1–December 31)

Patients must have a valid primary diagnosis code.
Exclusions:
Patients who began RRT for ESKD outside of Canada but are subsequently treated in Canada

</td></tr>
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<div role="button" class="expandableTitle" aria-controls="backgroundRegion">Background, Interpretation and Benchmarks</div>

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<tr><td>Rationale</td><td>

Disease etiology can be tracked by viewing changes in the primary diagnosis over time. There are significant costs associated with treating this patient group.

</td></tr>


<tr><td>Interpretation</td><td>

Increasing incidence rates over time have important implications for resources, disease management and the need for kidney donation.

</td></tr>

<tr><td>HSP Framework Dimension</td><td>

Health System Outcomes: Improve health status of Canadians

</td></tr>

<tr><td>Areas of Need</td><td>

Not applicable

</td></tr>

<tr><td>Targets/Benchmarks</td><td>

Not applicable

</td></tr>


<tr><td>References</td><td>

Nesrallah GE, Mustafa RA, Clark WF, et al. Canadian Society of Nephrology 2014 Clinical Practice Guideline for Timing the Initiation of Chronic Dialysis. CMAJ. 2014;186(2):112-117. Available at http://www.cmaj.ca/content/186/2/112

Levin A, Hemmelgarn B, Culleton B, et al. Guidelines for Management of Chronic Kidney Disease. CMAJ. 2008;179(11):1154-1162. Available at http://www.cmaj.ca/content/179/11/1154

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<div role="button" class="expandableTitle" aria-controls="availabilityRegion">Availability of Data Sources and Results</div>

<table id="availabilityRegion">

<tr><td>Data Sources</td><td>

CORR

</td></tr>

<tr><td>Available Data Years</td><td>

Type of Year:
Calendar
First Available Year:
2010
Last Available Year:
2019

</td></tr>

<tr><td>Geographic Coverage</td><td>

All provinces/territories except Quebec

</td></tr>


<tr><td>Reporting Level/Disaggregation</td><td>

Province/Territory, Breakdown by sex, breakdown by age categories

</td></tr>
</table>



<div role="button" class="expandableTitle" aria-controls="resultRegion">Result Updates</div>

<table id="resultRegion">

<tr><td>Update Frequency</td><td>

Every year

</td></tr>



<tr><td>Indicator Results</td><td>

Web Tool:
Quick Stats
URL:
Incident End-Stage Renal Disease (ESRD) Patients by Primary Diagnosis

</td></tr>

<tr><td>Updates</td><td>

Not applicable

</td></tr>
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<div role="button" class="expandableTitle" aria-controls="qualityRegion">Quality Statement</div>

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<tr><td>Caveats and Limitations</td><td>

The indicator is based on voluntary data submitted to CORR from facilities across Canada. Submission of data for patients beginning RRT for ESKD is not mandatory.

Data from Quebec was not included because of significant under-reporting between 2011 and 2019, which may lead to biased results.

</td></tr>


<tr><td>Trending Issues</td><td>

An overview of under-reporting of incident ESKD cases can be found in Data Quality Documentation for Users: Canadian Organ Replacement Register, 2010 to 2019 Data.

</td></tr>


<tr><td>Comments</td><td>

Not applicable

</td></tr>


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